Nintendo seeks to shake up gaming again with Wii U

LOS ANGELES (AP) — It can scan zombies, replace a TV remote, open a window into virtual worlds and shoot ninja stars across a living room. It’s the Wii U GamePad, the 10-by-5-inch touchscreen controller for the successor to the Wii out Sunday, and if you ask the brains behind the “Super Mario Bros.” about it, they say it’s going to change the way video games are made and played.

“You can’t manufacture buzz,” said Nintendo of America president Reggie Fils-Aime. “You can’t manufacture word of mouth. All we can do is to provide the product and the games to foster some sparks that hopefully enable that to happen. We think we have that with Wii U.”

Much like the iPad, the curvaceous GamePad features a touchscreen that can be manipulated with the simple tap or swipe of a finger, but it’s surrounded by the kinds of buttons, bumpers, thumbsticks and triggers that are traditionally found on a modern-day game controller. There’s also a camera, stylus, microphone, headphone jack and speakers.

While the Wii U can employ its predecessor’s motion-control remotes with a sensor bar that similarly detects them in front of the TV, the console’s focus on two-screen experiences makes it feel more like a high-definition, living-room rendition of the Nintendo DS and 3DS, the Japanese gaming giant’s dual-screen hand-held devices, than the original Wii.

“It’s a second screen like a tablet or a cellphone, but it’s different,” said Mark Bolas, professor of interactive media at the University of Southern California. “In addition to providing more information, the GamePad is also a second viewpoint into a virtual world. Nintendo is letting you turn away from the TV screen to see what’s happening with the GamePad.”

The touchscreen controller can also serve as a makeshift TV remote control and online video aggregator for services like Netflix and Amazon Instant Video. (Nintendo cheekily calls it TVii and announced Friday that it won’t be available until December.) Some games have the ability to flip-flop between the TV screen and the GamePad screen, allowing for non-gaming use of the TV.

There are limitations to the GamePad: it won’t work after it’s been moved 25 feet away from the Wii U console; it lasts about three to five hours after charging; and while its touchscreen is intuitive as those that have come before it, the GamePad is not quite as simple to use as the Wii controllers that had everyone bowling in their living rooms.

“Is the GamePad more complex than the Wii Remote was six years ago? Certainly,” said Fils-Aime. “On the other hand, I believe consumers will easily grasp the GamePad and what we’re trying to do with the varied experiences we’ll have not only at launch but over the next number of years in this system’s life.”

The abilities of the GamePad are most notably showcased by Nintendo Co. in the amusement park-themed mini-game collection “Nintendo Land,” which comes with the deluxe edition of the console. “Nintendo Land” turns the GamePad into several different tools, such as the dashboard of a spaceship or the ultimate advantage in a game of hide-and-seek.

In other titles, the controller mostly eliminates the need to pause the action to study a map in order to figure out where to go next or scour an inventory for just the right weapon. That can all be achieved simultaneously on the GamePad screen, which is best illustrated among the launch titles in Ubisoft’s survival action game “ZombiU.”

The GamePad acts as a high-tech scanner in “ZombiU” that can analyze a player’s surroundings in a version of London overrun by zombies. It pumps up the terror by drawing players’ attention away from the horrors lurking around them.

Will gamers who’ve grown up with their eyes glued to the TV and hands gripped on a controller adapt to glimpsing at another screen? The Wii U edition of “Call of Duty: Black Ops II,” for example, invites players to customize their arsenal on the fly on the GamePad, as well as engage in multiplayer matches without needing to split the TV in half.

Nintendo expects 50 games will be available for the Wii U by March 2013. There will be 23 games released alongside the console when it debuts Sunday, including the platformer “New Super Mario Bros. U,” karaoke game “Sing Party,” an “armored edition” of “Batman: Arkham City” and the Mickey Mouse adventure “Disney Epic Mickey 2: The Power of Two.”

“New consoles come along and nobody exploits their full capabilities for the first two to three years,” said Warren Spector, creative director at “Epic Mickey 2″ developer Junction Point Studios. “It’s only after you’ve had two or three projects that you fully understand what the hardware is capable of doing. We’re going to be experimenting with it more.”

Fils-Aime said he’s already envisioning ways that developers will innovate with future games. He pointed to some of the console’s features that aren’t on display in the launch line-up, such as the ability to play with two GamePads at once or utilize the console’s near-field communication technology to interact with other gadgets in the room.

“I think that developers and consumers are ready for new experiences,” said Fils-Aime. “More than anything else, I think that’s what is driving excitement for Wii U. They’ve experienced what this generation has to offer. They’re ready for something new.”

___

Online:

http://www.nintendo.com/wiiu

___

Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang.

Gaming News Headlines – Yahoo! News

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Rose McGowan's Dating Deal-Breaker: Sloppy Kisses

By Lilly Workneh

11/17/2012 at 05:25 PM EST

No need to find a secret spell on how to kiss Rose McGowan: The former Charmed star will tell you what she likes – and what she doesn't.

"Don't be sloppy!" McGowan, 39, tells PEOPLE. "That's the worst. You could find the hottest guy on the planet and if he's a bad kisser, it just doesn't work."

The actress hosted Cosmopolitan and Maybeline's Kisses for the Troops event on Monday in New York City and spilled the beans on what she considers to be a sexy smooch.

"I like the man to be medium aggressive, not somebody who's going to shove his tongue down your throat," she says. "That's not sexy."

Smooching comes with the territory for an actress says McGowan, who previously dated rocker Marilyn Manson and was engaged to filmmaker Robert Rodriguez.

"I had to kiss a lot of people on Charmed and I would kiss people I wouldn't even know. I'd say 'Hi, you're Ted? Let's make out Ted. Okay, Ted, it was really nice to meet you. I'll never see you again.' "

As far as kissing skills go, McGowan says guys shouldn't bother trying to learn too much. "I don't think you can teach somebody [to kiss]," she says. "You either just know how to do it or you don't."

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Wall Street Week Ahead: Going off "cliff" with a bungee cord

NEW YORK (Reuters) - The 1987 crash. The Y2K bug. The debt ceiling debacle of 2011.

All these events, in the end, turned out to be buying opportunities for stocks. So will the "fiscal cliff," some investors say as they watch favorite stocks tumble during the political give-and-take happening in Washington.

The first round of talks aimed at avoiding the "fiscal cliff" caused a temporary rise in equities on Friday, signaling Wall Street's recent declines could be a buying opportunity. The gains were small and sentiment remains weak, but it suggests hope for market bulls.

Though shares ended moderately higher on Friday, it was not enough to offset losses for the week. The S&P was down 1.5 percent, while both the Dow and the Nasdaq fell 1.8 percent.

The S&P 500 is down more than 5 percent in the seven sessions that followed President Barack Obama's re-election. Uncertainty arose as attention turned to Washington's task of dealing with mandated tax hikes and spending cuts that could take the U.S. economy back into recession.

Some see the market's move as an overreaction to hyperbolic headlines about policy gridlock in Washington, believing stocks may start to rebound in what should be a quiet few days ahead of the Thanksgiving holiday next Thursday.

"It just doesn't seem to make any sense that you suddenly wake up the day after the election and realize we've got a fiscal cliff," said Krishna Kumar, partner at New York hedge fund Goose Hollow Alpha Advisors.

Not long ago the S&P was on target for its second-best year in the last 10, riding a 17 percent advance in 2012. That's been halved to about 8 percent, which isn't bad but disappointing compared with just a month ago.

Investors have been selling the year's winners. Apple is down 25 percent from its peak above $700. General Electric is down 14 percent; Google has lost 16 percent. Overall, the stocks that make up the top 10 percent of performers in the month prior to Election Day have been the worst performers since, according to Bespoke Investment Group of Harrison, New York.

"I think it's a good opportunity to be long stocks at these levels," said Kumar.

Hikes on capital gains and dividend taxes are on the line, and Obama has dug in his heels on what he sees as a mandate to make the tax code more progressive.

He seems to have the upper hand in dealings with Congress because Republican lawmakers don't want to see tax rates increase, which is what will happen if no solution is found by the beginning of 2013. Republicans don't want to take the blame for driving the economy over the cliff.

The current crisis is similar to last year's fight to raise the U.S. debt ceiling, which led to the downgrade of the United States' top credit rating in early August 2011.

During the dealings, the S&P 500 lost 18.8 percent between its peak in July 2011 and its bottom in August. As the market slid, the political standoff badly hurt investors' confidence in Washington, setting off a spike in volatility.

In the end a deal was announced that raised the ceiling and put off longer-term fiscal decisions until January 1, 2013, setting the stage for today's "fiscal cliff" crisis.

After staying flat through September 2011, the S&P 500 jumped 31 percent between its October low and the end of March.

BUY THE DIP?

Gridlock in Washington and all that could possibly go wrong with the economy if a deal is not reached have grabbed the headlines, but the negotiations leave room for stock market gains. Congressional leaders said Friday they will work through the Thanksgiving holiday recess to find a solution.

"The debate over how to solve (the fiscal cliff) may be more productive than is commonly recognized," said Brad Lipsig, senior portfolio manager at UBS Financial Services in New York.

"The U.S. is facing a major debt overhang, and serious steps toward addressing it might ultimately be viewed as a positive for future growth," he said. "The market may recognize this and, after a time of hand wringing, recover from the concerns with a renewed sense of optimism."

The recent selling took the S&P 500's relative strength index - a technical measure of internal strength - below 30 this week, indicating the benchmark is oversold and due for a rebound.

The RSI in four of the 10 S&P sectors - utilities, telecoms, consumer staples and technology - is below 30 and the highest RSI reading, for the consumer discretionary sector, is below 40, suggesting a bounce is in store.

"What I want to do is what we did during the decline following the budget negotiations in the summer of 2011: The lower the stock market goes, the more I want to own stock," said Brian Reynolds, chief market strategist at New York-based Rosenblatt Securities.

"If we go off the cliff it will be with a bungee cord attached," he said.

KEEP CALM AND HEDGE

Volatility is expected to rise through the end of November and to spike in late December if no agreement on the fiscal cliff is reached in Congress. Alongside comes opportunity for those with high risk tolerance.

"Recently, volatility has increased in the market overall. You can't really pick it up in the VIX yet, but I think as we get through November, I think you're likely to see the VIX be at a relatively higher level," said Bruce Zaro, chief technical strategist at Delta Global Asset Management in Boston.

In 2011, the VIX averaged 19.2 in July and 35 in August. So far this month the average is 17.8 and it is expected to spike if negotiations on the cliff drag into late next month.

"Looking at the range of possibilities, I would say any of them would be better than sitting here waiting. I would even put going off the fiscal cliff in that category," said Jill Cuniff, president of Seattle-based Edge Asset Management Inc, which manages about $20 billion.

"But we don't believe Congress will let that happen; there's going to be some middle ground here."

(Reporting by Rodrigo Campos and Jonathan Spincer, additional reporting by Caroline Valetkevitch; Editing by Kenneth Barry)

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Israel hits Hamas buildings, shoots down Tel Aviv-bound rocket

GAZA/JERUSALEM (Reuters) - Israeli aircraft bombed Hamas government buildings in Gaza, and the "Iron Dome" defense system shot down a Tel Aviv-bound rocket on Saturday as Israel geared up for a possible ground invasion.

Hamas, the Palestinian Islamist group that runs the Gaza Strip, said Israeli missiles wrecked the office building of Prime Minister Ismail Haniyeh - where he had met on Friday with the Egyptian prime minister - and struck a police headquarters.

Along the Tel Aviv beachfront, volleyball games came to an abrupt halt and people crouched as sirens sounded. Two interceptor rockets streaked into the sky. A flash and an explosion followed as Iron Dome, deployed only hours earlier near the city, destroyed the incoming projectile in mid-air.

With Israeli tanks and artillery positioned along the Gaza border and no end in sight to hostilities now in their fourth day, Tunisia's foreign minister travelled to the enclave in a show of Arab solidarity.

In Cairo, a presidential source said Egyptian President Mohamed Mursi would hold four-way talks with the Qatari emir, the prime minister of Turkey and Hamas chief Khaled Meshaal in the Egyptian capital on Saturday to discuss the Gaza crisis.

Egypt has been working to reinstate calm between Israel and Hamas after an informal ceasefire brokered by Cairo unraveled over the past few weeks. Meshaal, who lives in exile, has already held a round of talks with Egyptian security officials.

Officials in Gaza said 43 Palestinians, nearly half of them civilians including eight children, had been killed since Israel began its air strikes. Three Israeli civilians were killed by a rocket on Thursday.

Israel unleashed its massive air campaign on Wednesday with the declared goal of deterring Hamas from launching rockets that have plagued its southern communities for years.

The Israeli army said it had zeroed in on a number of government buildings during the night, including Haniyeh's office, the Hamas Interior Ministry and a police compound.

Taher al-Nono, a spokesman for the Hamas government, held a news conference near the rubble of the prime minister's office and pledged: "We will declare victory from here."

Hamas's armed wing claimed responsibility for Saturday's rocket attack on Tel Aviv, the third against the city since Wednesday. It said it fired an Iranian-designed Fajr-5 at the coastal metropolis, some 70 km (43 miles) north of Gaza.

"Well that wasn't such a big deal," said one woman, who had watched the interception while clinging for protection to the trunk of a baby palm tree on a traffic island.

In the Israeli Mediterranean port of Ashdod, a rocket ripped into several balconies. Police said five people were hurt.

Among those killed in airstrikes on Gaza on Saturday were at least four suspected militants riding on motorcycles.

Israel's operation has drawn Western support for what U.S. and European leaders have called Israel's right to self-defense, along with appeals to avoid civilian casualties.

Hamas, shunned by the West over its refusal to recognize Israel, says its cross-border attacks have come in response to Israeli strikes against Palestinian fighters in Gaza.

RESERVIST CALL-UP

At a late night session on Friday, Israeli cabinet ministers decided to more than double the current reserve troop quota set for the Gaza offensive to 75,000, political sources said, in a signal Israel was edging closer to an invasion.

Around 16,000 reservists have already been called up.

Asked by reporters whether a ground operation was possible, Major-General Tal Russo, commander of the Israeli forces on the Gaza frontier, said: "Definitely."

"We have a plan ... it will take time. We need to have patience. It won't be a day or two," he added.

A possible move into the densely populated Gaza Strip and the risk of major casualties it brings would be a significant gamble for Prime Minister Benjamin Netanyahu, favorite to win a January national election.

Hamas fighters are no match for the Israeli military. The last Gaza war, involving a three-week long Israeli air blitz and ground invasion over the New Year period of 2008-09, killed over 1,400 Palestinians, mostly civilians. Thirteen Israelis died.

But the Gaza conflagration has stirred the pot of a Middle East already boiling from two years of Arab revolution and a civil war in Syria that threatens to spread beyond its borders.

"Israel should understand that many things have changed and that lots of water has run in the Arab river," Tunisian Foreign Minister Rafik Abdesslem said as he surveyed the wreckage from a bomb-blast site in central Gaza.

One major change has been the election of an Islamist government in Cairo that is allied with Hamas, potentially narrowing Israel's manoeuvering room in confronting the Palestinian group. Israel and Egypt made peace in 1979.

"DE-ESCALATION"

Netanyahu spoke late on Friday with U.S. President Barack Obama for the second time since the offensive began, the prime minister's office said in a statement.

"(Netanyahu) expressed his deep appreciation for the U.S. position that Israel has a right to defend itself and thanked him for American aid in purchasing Iron Dome batteries," the statement added.

The two leaders have had a testy relationship and have been at odds over how to curb Iran's nuclear program.

A White House official said on Saturday Obama called Turkish Prime Minister Tayyip Erdogan to discuss how the two countries could help bring an end to the Gaza conflict.

Ben Rhodes, White House deputy national security adviser, told reporters that Washington "wants the same thing as the Israelis want", an end to rocket attacks from Gaza. He said the United States is emphasizing diplomacy and "de-escalation".

In Berlin, a spokesman for German Chancellor Angela Merkel said she had spoken to Netanyahu and Egypt's Mursi, stressing to the Israeli leader that Israel had a right to self-defense and that a ceasefire must be agreed as soon as possible to avoid more bloodshed.

U.N. Secretary-General Ban Ki-moon is expected to visit Israel and Egypt next week to push for an end to the fighting in Gaza, U.N. diplomats said on Friday.

The Israeli military said 492 rockets fired from Gaza have hit Israel since the operation began. Iron Dome intercepted another 245.

In Jerusalem, targeted by a Palestinian rocket on Friday for the first time in 42 years, there was little outward sign on the Jewish Sabbath that the attack had any impact on the usually placid pace of life in the holy city.

Some families in Gaza have abandoned their homes - some of them damaged and others situated near potential Israeli targets - and packed into the houses of friends and relatives.

(Additional reporting by Dan Williams and Douglas Hamilton in Tel Aviv, Allyn Fisher-Ilan in Jerusalem, Jeff Mason aboard Air Force One, Writing by Jeffrey Heller; editing by Crispian Balmer)

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Pittsburgh airport to offer free ‘cell phone’ lot

IMPERIAL, Pa. (AP) — Pittsburgh International Airport is offering free parking for folks who want to sit in their cars and wait for arriving passengers to call on cell phones to say they’ve arrived.

Allegheny County Airport Authority officials are hoping the plan will prevent motorists from congesting the curb near the airport’s terminal or the access roads around it by driving around in circles waiting for cell phone calls from arrivals.

Drivers can now park free for an hour in the extended term lot farthest from the terminal, and pay only $ 1 for a second hour of parking. After two hours, the spots will cost $ 8.

Gadgets News Headlines – Yahoo! News

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Robert Pattinson Wanted to Put Walruses in Breaking Dawn Sex Scene

People Pets

11/16/2012 at 06:30 PM EST

Robert Pattinson

Picture Perfect/REX; Getty

Those pillow-biting sex scenes are about to get even hotter now that Kristen Stewart's onscreen alter ego Bella Swan is a full-blown, cold-blooded vampire in the final installment of the Twilight saga.

But if it were up to Robert Pattinson, who plays Bella's husband Edward Cullen, the bedroom action would get even wilder.

"I would put [the sex scene] the last day of the schedule," he told BBC Radio 1 of his fantasy turn in the director's chair. "[I'd] say, 'Listen, I've got to have a closed set. It's really, really important. No one can see the monitors or anything,' and then just put like a walrus in or something."

Jokes aside, it's not so sexy puckering up in front of the cameras.

"Kissing is harder than love-making scenes, I think," Pattinson, 26, says. "You can't kiss like normally you'd kiss."

Adds The Twilight Saga: Breaking Dawn – Part 2 star, whose movie arrives in theaters Friday: "You got a one in three chance of smashing someone's tooth out."

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Wal-Mart files U.S. labor charge against union

(Reuters) - Wal-Mart Stores Inc is taking its first legal step to stop months of protests and rallies outside Walmart stores, targeting the union that it says is behind such actions.

Wal-Mart filed an unfair labor practice charge against the United Food and Commercial Workers International Union, or UFCW, asking the National Labor Relations Board to halt what the retailer says are unlawful attempts to disrupt its business.

The move comes just a week before what is expected to be the largest organized action against the world's largest retailer, as a small group of Walmart workers prepare to strike on Black Friday, typically the busiest shopping day of the year.

"We are taking this action now because we cannot allow the UFCW to continue to intentionally seek to create an environment that could directly and adversely impact our customers and associates," Wal-Mart spokesman David Tovar said on Friday. "If they do, they will be held accountable."

The union is undeterred. "Walmart is grasping at straws," said UFCW Communications Director Jill Cashen. "There's nothing in the law that gives an employer the right to silence workers and citizens."

Protests and rallies outside Walmart stores around the country and other actions such as flash mobs have been orchestrated by groups including OUR Walmart, a coalition of thousands of Walmart workers that wants to collectively push for better wages, benefits and working conditions.

"Wal-Mart is in effect firing a shot across the bow of the UFCW, essentially saying 'Look, you can expect this and more unless you desist,'" said Harley Shaiken, a professor at the University of California, Berkeley, who specializes in labor issues.

Filing with the NLRB suggests that the protests have caught the attention of Wal-Mart, which has no union-represented workers in the United States.

OUR Walmart and another group, Making Change at Walmart, are affiliated with the UFCW, which represents more than 1 million workers including many at retailers that compete with Walmart. According to a filing with the Labor Department, OUR Walmart was a subsidiary of the UFCW as of 2011. It is unclear whether it remains a subsidiary or has legally separated from the union.

"The fact that Wal-Mart is responding in such a public way is itself both unusual and indicative that they truly don't want to see this spread," Shaiken said.

The NLRB typically receives a charge and investigates. At times, it resolves issues without issuing a complaint, spokesman Tony Wagner said. While most investigations take about six weeks, they can be expedited under certain criteria, he said.

Activities over the past year or longer "have caused disruptions to Walmart's business, resulted in misinformation being shared publicly about our company, and created an uncomfortable environment and undue stress on Walmart's customers, including families with children," Walmart outside counsel Steven Wheeless said in a letter sent on Friday to Deborah Gaydos, assistant general counsel of the UFCW.

PICKETING PROHIBITED

The National Labor Relations Act prohibits such picketing for more than 30 days without the filing of a representation petition. The NLRA also requires the NLRB to seek a federal court injunction against such activity, the letter states.

The OUR Walmart group of current and former Walmart employees has been organizing 1,000 protests including strikes and what it called online actions that began this week and will culminate on Black Friday.

For example, workers walked off the job in Seattle on Thursday and in Dallas on Friday, OUR Walmart said.

Bentonville, Arkansas-based Wal-Mart said that anyone who is not an employee is prohibited from coming onto its owned or controlled parking lots or other facilities to solicit, hand out literature or otherwise engage in any demonstration.

Wal-Mart said that it intends for the UFCW to be held accountable for any injury or property damage that may occur as a result of the actions led by the union, OUR Walmart or any of its other affiliates.

Past attempts to unionize Walmart U.S. workers have failed. In 2005, Tire and Lube Express department workers at stores in New Castle, Pennsylvania, and Loveland, Colorado, voted against representation by the UFCW.

OUR Walmart is not a union, though the thousands of Walmart employees it says are members do pay $5 monthly dues.

Wal-Mart has 1.4 million U.S. workers. Of 5 million job applications Walmart U.S. received in 2011, 20 percent of the workers it hired were coming back to the company. The turnover rate among Walmart U.S. employees, 37.26 percent in 2011, was below the industry average of 43.6 percent, it says.

"We just don't think what the unions have to offer is a better deal for our associates," said Wal-Mart's Tovar.

Wal-Mart filed its charge against the UFCW late on Thursday with the NLRB regional office in Little Rock, Arkansas. The case number is 26-CB-093342.

For copies of Wal-Mart's letter to the UFCW and the NLRB charge document click http://bit.ly/Qj5c0t and http://bit.ly/RZoNkD

(Reporting by Jessica Wohl in Chicago; Editing by Tim Dobbyn and Leslie Gevirtz)

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Israel authorizes more reservists after rockets target cities

GAZA/JERUSALEM (Reuters) - Israel's cabinet authorized the mobilization of up to 75,000 reservists late on Friday, preparing the ground for a possible Gaza invasion after Palestinians fired a rocket toward Jerusalem for the first time in decades.

Tel Aviv, Israel's commercial centre, also came under rocket attack for the second straight day, in defiance of an Israeli air offensive that began on Wednesday with the declared aim of deterring Hamas from launching cross-border attacks that have plagued southern Israel for years.

Hamas, the Islamist group that runs the Gaza Strip, claimed responsibility for firing at Jerusalem and Tel Aviv. Israel said the rocket launched toward Jerusalem landed in the occupied West Bank, and the one fired at Tel Aviv did not hit the city. There were no reports of casualties.

The siren that sounded in Jerusalem stunned many Israelis. The city, holy to Jews, Muslims and Christians, was last struck by a Palestinian rocket in 1970, and it was not a target when Saddam Hussein's Iraq fired missiles at Israel in the 1991 Gulf War.

Prime Minister Benjamin Netanyahu held a four-hour strategy session with a clutch of senior ministers in Tel Aviv on widening the military campaign, while other cabinet members were polled by telephone on raising the mobilization level.

Political sources said they decided to more than double the current reserve troop quota set for the Gaza offensive to 75,000. The move did not necessarily mean all would be called into service.

Hours earlier, Egypt's prime minister, denouncing what he described as Israeli aggression, visited Gaza and said Cairo was prepared to mediate a truce.

Officials in Gaza said 29 Palestinians - 13 militants and 16 civilians, among them eight children and a pregnant woman - had been killed in the enclave since Israel began its air strikes. Three Israeli civilians were killed by a rocket on Thursday.

The Israeli military said 97 rockets fired from Gaza hit Israel on Friday and 99 more were intercepted by its Iron Dome anti-missile system. Dozens of Israeli bombing raids rocked the enclave, and one flattened the Gaza Interior Ministry building.

In a further sign Netanyahu might be clearing the way for a ground operation, Israel's armed forces announced that a highway leading to the territory and two roads bordering the enclave of 1.7 million Palestinians would be off-limits to civilian traffic.

Tanks and self-propelled guns were seen near the border area on Friday, and the military said it had already called 16,000 reservists to active duty.

Netanyahu is favorite to win a January national election, but further rocket strikes against Tel Aviv, a free-wheeling city Israelis equate with New York, and Jerusalem, which Israel regards as its capital, could be political poison for the conservative leader.

"The Israel Defence Forces will continue to hit Hamas hard and are prepared to broaden the action inside Gaza," Netanyahu said before the rocket attacks on the two cities.

Asked about Israel massing forces for a possible Gaza invasion, Hamas spokesman Sami Abu Zuhri said: "The Israelis should be aware of the grave results of such a raid, and they should bring their body bags."

SOLIDARITY VISIT

A solidarity visit to Gaza by Egyptian Prime Minister Hisham Kandil, whose Islamist government is allied with Hamas but also party to a 1979 peace treaty with Israel, had appeared to open a tiny window to emergency peace diplomacy.

Kandil said: "Egypt will spare no effort ... to stop the aggression and to achieve a truce."

But a three-hour truce that Israel declared for the duration of Kandil's visit never took hold.

Israel Radio's military affairs correspondent said the army's Homefront Command had told municipal officials to make civil defence preparations for the possibility that fighting could drag on for seven weeks. An Israeli military spokeswoman declined to comment on the report.

The Gaza conflagration has stoked the flames of a Middle East already ablaze with two years of Arab revolution and a civil war in Syria that threatens to leap across borders.

It is the biggest test yet for Egypt's new President Mohamed Mursi, a veteran Islamist politician from the Muslim Brotherhood who was elected this year after last year's protests ousted military autocrat Hosni Mubarak.

Egypt's Muslim Brotherhood are spiritual mentors of Hamas, yet Mursi has also pledged to respect Cairo's 1979 peace treaty with Israel, seen in the West as the cornerstone of regional security. Egypt and Israel both receive billions of dollars in U.S. military aid to underwrite their treaty.

Mursi has vocally denounced the Israeli military action while promoting Egypt as a mediator, a mission that his prime minister's visit was intended to further.

A Palestinian official close to Egypt's mediators told Reuters Kandil's visit "was the beginning of a process to explore the possibility of reaching a truce. It is early to speak of any details or of how things will evolve".

Hamas fighters are no match for the Israeli military. The last Gaza war, involving a three-week long Israeli air blitz and ground invasion over the New Year period of 2008-2009, killed more than 1,400 Palestinians, mostly civilians. Thirteen Israelis died.

Tunisia's foreign minister was due to visit Gaza on Saturday "to provide all political support for Gaza" the spokesman for the Tunisian president, Moncef Marzouki, said in a statement.

The United States asked countries that have contact with Hamas to urge the Islamist movement to stop its rocket attacks.

Hamas refuses to recognize Israel's right to exist. By contrast, Palestinian President Mahmoud Abbas, who rules in the nearby West Bank, does recognize Israel, but peace talks between the two sides have been frozen since 2010.

Abbas's supporters say they will push ahead with a plan to have Palestine declared an "observer state" rather than a mere "entity" at the United Nations later this month.

(Additional reporting by Maayan Lubell, Jeffrey Heller and Crispian Balmer in Jerusalem; Writing by Jeffrey Heller; Editing by Giles Elgood and Will Waterman)

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Sina’s profit beats on Weibo; co forecasts weak 4th-quarter revenue

(Reuters) – Chinese internet company Sina Corp eked out a profit in the third quarter that beat analysts’ estimates as strong advertising sales on its microblogging platform offset weaker website advertising but it forecast current-quarter revenue below expectations.

Shares of the company fell 6 percent to $ 49.72 in extended trading. They closed at $ 53.10 on the Nasdaq on Thursday.

Sina expects adjusted net revenue to range between $ 132 million and $ 136 million in the fourth quarter, with advertising revenues forecast to increase between 6 percent and 8 percent from a year earlier.

Analysts on average were expecting revenue of $ 151.9 million, according to Thomson Reuters I/B/E/S.

Sina, which makes most of its revenue from online advertising both on its website and through its microblogging platform, Weibo, is facing stiff headwinds this year as firms slash advertising budgets due to a worsening economic outlook.

Analysts said the spat between Japan and China over a few uninhabited islands in the East China Sea may have affected Sina’s website advertising sales as Japanese automakers cut back on advertising in China.

Net profit was $ 9.9 million for the September quarter, compared to a loss of $ 336.3 million a year earlier. The profit beat analysts’ expectations of $ 7.5 million.

Sina’s advertising revenue rose 19 percent to $ 120.6 million in the third quarter, while non-advertising revenue rose 9 percent to $ 31.8 million. Overall net revenue was $ 152.4 million, up from $ 130.3 million, a year earlier.

The company started monetizing Weibo by offering special services to business accounts and selling VIP memberships to regular users earlier this year.

Weibo contributed about 10 percent to total advertising revenue in the second quarter and had 368 million registered accounts.

(Reporting By Melanie Lee in Shanghai & Aurindom Mukherjee in Bangalore; Editing by Sriraj Kalluvila)

Internet News Headlines – Yahoo! News

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Cesar Millan Reveals: I Attempted Suicide

People Pets

11/15/2012 at 06:30 PM EST

Cesar Millan with dog Daddy

Meredith Jenks

It seemed Cesar Millan had been on top of the world, but then it all came crashing down.

In 2010, the trainer and television personality known as the Dog Whisperer was working with celebrity clients, had a hit show and was becoming an international advocate for bully breeds.

Millan, 43, was dealt his first loss when Daddy, the 16-year-old pit bull who had been Millan's best example of a "calm, submissive" dog, died in February.

Then, in June of that year, Millan learned that his wife of 16 years, Ilusion Millan, had filed for divorce.

"I was at the lowest level I had ever been emotionally and psychologically," Millan wrote on his blog in August of this year.

So low, in fact, that he attempted suicide, a revelation Millan makes in Cesar Millan: The Real Story, a documentary airing on Nat Geo Wild on Nov. 25.

"Daddy was my Tibet, my Himalaya, my Gouda, my Buddha, my source of calmness," Millan tells the Associated Press.

After surviving the overdose, Millan opted for work, exercise and affection over antidepressants. His recovery progressed further when he met Jahira Dar, a woman Millan calls "the one."

He plans to propose soon. "I am a traditional guy, so I like to do the whole parent thing," Millan said. "I know they are going to say yes, but I like the whole Cinderella story."

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Diabetes rates rocket in Oklahoma, South

NEW YORK (AP) — The nation's diabetes problem is getting worse, and the biggest jump over 15 years was in Oklahoma, according to a new federal report issued Thursday.

The diabetes rate in Oklahoma more than tripled, and Kentucky, Georgia and Alabama also saw dramatic increases since 1995, the study showed.

The South's growing weight problem is the main explanation, said Linda Geiss, lead author of the report by the Centers for Disease Control and Prevention study.

"The rise in diabetes has really gone hand in hand with the rise in obesity," she said.

Bolstering the numbers is the fact that more people with diabetes are living longer because better treatments are available.

The disease exploded in the United States in the last 50 years, with the vast majority from obesity-related Type 2 diabetes. In 1958, fewer than 1 in 100 Americans had been diagnosed with diabetes. In 2010, it was about 1 in 14.

Most of the increase has happened since 1990.

Diabetes is a disease in which the body has trouble processing sugar; it's the nation's seventh leading cause of death. Complications include poor circulation, heart and kidney problems and nerve damage.

The new study is the CDC's first in more than a decade to look at how the nationwide boom has played out in different states.

It's based on telephone surveys of at least 1,000 adults in each state in 1995 and 2010. Participants were asked if a doctor had ever told them they have diabetes.

Not surprisingly, Mississippi — the state with the largest proportion of residents who are obese — has the highest diabetes rate. Nearly 12 percent of Mississippians say they have diabetes, compared to the national average of 7 percent.

But the most dramatic increases in diabetes occurred largely elsewhere in the South and in the Southwest, where rates tripled or more than doubled. Oklahoma's rate rose to about 10 percent, Kentucky went to more than 9 percent, Georgia to 10 percent and Alabama surpassed 11 percent.

An official with Oklahoma State Department of Health said the solution is healthier eating, more exercise and no smoking.

"And that's it in a nutshell," said Rita Reeves, diabetes prevention coordinator.

Several Northern states saw rates more than double, too, including Washington, Idaho, Montana, Wyoming, South Dakota, Minnesota, Missouri, Ohio and Maine.

The study was published in CDC's Morbidity and Mortality Weekly Report.

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Associated Press writer Ken Miller in Oklahoma City contributed to this report.

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Online:

CDC report: http://tinyurl.com/cdcdiabetesreport

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Wall Street ends flat as wary investors stay defensive

NEW YORK (Reuters) - Stocks were little changed on Thursday as the prospect of a drawn-out battle over impending tax and spending changes made investors wary of getting into the water, while retailer Wal-Mart tumbled after disappointing sales.

The S&P 500 is down nearly 2 percent for the week, adding to last week's selloff and eroding more of the market's gains for the year.

What had looked like a stellar 2012 for stocks has turned into merely an average year, and as 2012 draws to a close, investors are becoming more inclined to protect the gains they have.

The worry is the economy could contract again if no deal is reached in Washington to avoid the "fiscal cliff" - large, automatic budget cuts and tax hikes that begin to take effect in the new year.

Combined with the euro zone debt crisis, the uncertain outlook for corporations makes it hard to know how much a stock is worth, said Alan Lancz, president of Alan B. Lancz & Associates in Toledo, Ohio.

"Valuation is going to be uncertain because you don't know what the growth will be," said Lancz. "That is definitely not a good scenario for someone to step up to the plate and do a lot of buying."

The euro zone relapsed into its second recession since 2009 in the third quarter as the region was hurt by its debt problems.

Wal-Mart fell 3.6 percent to $68.72 and was the biggest drag on the Dow as frugal consumers hurt the company's quarterly sales.

Investors will be watching Friday's meeting at the White House between President Barack Obama and Republican and Democratic leaders of Congress over deficit reduction for any sign the two sides are moving closer.

The memory of last year's political impasse over raising the debt ceiling has also made analysts nervous.

"(There is) uncertainty of whether we're going to have a functioning government going forward. That is a weight that sits on markets right now," said Troy Logan, managing director and senior economist at Warren Financial Service in Exton, Pennsylvania.

Even if the economy avoids an outright recession, there are fears a lengthy political dispute could sap business investment and consumer spending.

The Dow Jones industrial average <.dji> slipped 28.49 points, or 0.23 percent, to 12,542.46. The Standard & Poor's 500 Index <.spx> lost 2.16 points, or 0.16 percent, to 1,353.33. The Nasdaq Composite Index <.ixic> was off 9.87 points, or 0.35 percent, to 2,836.94.

The S&P 500 sunk to a 3 1/2-month closing low and was well below its 200-day moving average, which it pierced last week.

Data on Thursday showed new claims for unemployment benefits surged last week, while factory activity in the mid-Atlantic region unexpectedly shrank in November as the economy felt the effects of superstorm Sandy.

A flare-up in violence in the Middle East added to market unease as Israeli warplanes bombed targets in and around Gaza city for a second day, while two rockets fired from the Gaza Strip targeted Tel Aviv.

Apple Inc shares dragged the Nasdaq lower, falling 2.1 percent to $525.62 and down about 25 percent since September's high.

Also in the tech sector, shares of Dell Inc fell in after-hours trading after it reported revenue that was shy of Wall Street's expectations. Dell was down 2.2 percent at $9.35.

Target Corp bucked the trend, rising 1.7 percent to $62.44 after it reported a profit that beat expectations.

Volume was roughly 7.26 billion shares on the New York Stock Exchange, the Nasdaq and the NYSE MKT, topping the year-to-date average daily closing volume of around 6.5 billion.

Decliners outnumbered advancers on the NYSE by 2,069 to 975 on the New York Stock Exchange. Decliners also had the upper hand on the Nasdaq, outpacing advancers 1,506 to 948.

(Editing by Kenneth Barry)

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Rockets hit near Tel Aviv as Gaza death toll rises

GAZA (Reuters) - Two rockets fired from the Gaza Strip targeted Tel Aviv on Thursday in the first attack on Israel's commercial capital in 20 years, raising the stakes in a showdown between Israel and the Palestinians that is moving towards all-out war.

Earlier, a Hamas rocket killed three Israelis north of the Gaza Strip, drawing the first blood from Israel as the Palestinian death toll rose to 19, six of them children.

Israeli warplanes bombed targets in and around Gaza city for a second day, shaking tall buildings. In a sign of possible escalation, the armed forces spokesman said the military had received the green light to call in up to 30,000 reserve troops.

Plumes of smoke and dust furled into a sky laced with the vapor trails of outgoing rockets over the crowded city, where four young children killed on Wednesday were buried.

Israeli Defence Minister Ehud Barak said Palestinian militants would pay a price for firing the missiles.

In the latest air strikes, three people were killed when a missile hit their car in the northern Gaza Strip. The Israeli military also said it had carried out aerial attacks and had destroyed 70 unmanned missile launch sites.

An electricity generator supplying the home of Hamas prime minister Ismail Haniyeh by the Gaza shore was one of the sites hit by Israeli missiles.

The conflict, launched by Israel with the killing of Hamas's military chief, pours oil on the fire of a Middle East already ablaze with two years of revolution and an out-of-control civil war in Syria.

Israel says its attack is in response to escalating missile strikes from Gaza. Israel's bombing has not yet reached the saturation level seen before it last invaded Gaza in 2008, but Israeli officials have said a ground assault is still possible.

Egypt's new Islamist President Mohamed Mursi, viewed by Hamas as an ally, led a chorus of denunciation of the Israeli strikes by Palestinian allies.

Mursi's prime minister, Hisham Kandil, will visit Gaza on Friday with other Egyptian officials in a show of support for the enclave, an Egyptian cabinet official said. Israel promised that the delegation would come to no harm.

MISSILE STRIKES

Israeli police said three Israelis died when a rocket hit a four-story building in the town of Kiryat Malachi, 25 km (15 miles) north of Gaza, the first Israeli fatalities of the latest conflict to hit the coastal region.

Air raid sirens sent residents running for shelter in Tel Aviv, a Mediterranean city that has not been hit by a rocket since the 1991 Gulf War. Israeli sources said one rocket landed in the sea, while another landed in an uninhabited area of the Tel Aviv suburbs.

The Tel Aviv metropolitan area holds more than 3 million people, more than 40 percent of Israel's population.

"This escalation will exact a price that the other side will have to pay," Barak said in a television broadcast shortly after the strike.

Speaking at the same time in Gaza, Hamas leader Haniyeh urged Egypt to do more to help the Palestinians.

"We call upon the brothers in Egypt to take the measures that will deter this enemy," the Hamas prime minister said.

After watching powerlessly from the sidelines of the Arab Spring, Israel has been thrust to the centre of a volatile new world in which Islamist Hamas hopes that Mursi and his newly dominant Muslim Brotherhood in Egypt will be its protectors.

"The Israelis must realize that this aggression is unacceptable and would only lead to instability in the region and would negatively and greatly impact the security of the region," Mursi said.

The new conflict will be the biggest test yet of Mursi's commitment to Egypt's 1979 peace treaty with Israel, which the West views as the bedrock of Middle East peace.

The Muslim Brotherhood, which brought Mursi to power in an election after the downfall of Hosni Mubarak, has called for a "Day of Rage" in Arab capitals on Friday.

ASSASSINATION

The Gaza offensive began on Wednesday when a precision Israeli air strike killed Hamas military mastermind Ahmed Al-Jaabari. Israel then began shelling the enclave from land, air and sea.

At Jaabari's funeral on Thursday, supporters fired guns in the air celebrating news of the Israeli deaths, to chants for Jaabari of "You have won."

His corpse was borne through the streets wrapped in a bloodied white sheet. But senior Hamas figures were not in evidence, wary of Israel's warning they are in its crosshairs.

The Israeli army said 250 targets were hit in Gaza, including more than 130 rocket launchers. It said more than 270 rockets had struck Israel since the start of the operation, with its Iron Dome interceptor system shooting down more than 105 rockets headed for residential areas.

Expecting days or more of fighting and almost inevitable civilian casualties, Israeli warplanes dropped leaflets in Gaza telling residents to stay away from Hamas and other militants.

The United States has asked countries that have contact with Hamas to urge the group to stop its rocket attacks from Gaza, a White House adviser said.

"We've ... urged those that have a degree of influence with Hamas such as Turkey, and Egypt and some of our European partners to use that influence to urge Hamas to de-escalate," said Ben Rhodes, deputy national security adviser, in a conference call with reporters.

French President Francois Hollande has begun talks with Israeli Prime Minister Benjamin Netanyahu and other world leaders in an attempt to avert an escalation of violence in the Gaza Strip, Prime Minister Jean-Francois Ayrault said.

British Prime Minister David Cameron also spoke to Netanyahu, saying Hamas bore the principal responsibility for the crisis.

"GATES OF HELL"

Israel's sworn enemy Iran, which supports and arms Hamas, condemned the Israeli offensive as "organized terrorism". Lebanon's Iranian-backed Shi'ite militia Hezbollah, which has its own rockets aimed at the Jewish state, denounced strikes on Gaza as "criminal aggression", but held its fire. The Organisation of Islamic Cooperation condemned Israel's action.

Oil prices rose more than $1 as the crisis grew. Israeli shares and bonds fell, while Israel's currency rose off Wednesday's lows, when the shekel slid more than 1 percent to a two-month low against the dollar.

A second Gaza war has loomed on the horizon for months as waves of Palestinian rocket attacks and Israeli strikes grew increasingly intense and frequent. Netanyahu, favored in polls to win a January 22 general election, said the Gaza operation could be stepped up.

Hamas has said the killing of its top commander in a precise, death-from-above air strike, would "open the gates of hell" for Israel.

(Additional reporting by Jeffrey Heller in Jerusalem, Erika Solomon in Beirut, John Irish in Paris. Marwa Awad in Cairo.; Writing by Douglas Hamilton; Editing by Crispian Balmer and Giles Elgood)

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Steve Wozniak, Danny Trejo to appear in 8-bit video game

LOS ANGELES (TheWrap.com) – When it comes to the iPhone, Steve Jobs created it, but Steve Wozniak got game.

The Apple co-founder will appear as a playable character in an upcoming iOS video game “Danny Trejo‘s Vengeance: Woz with a Coz.”

The game, slated to be released around November 22, puts Wozniak alongside “Machete” star Trejo in an 8-bit mobile game, fighting a city full of enemies with an assortment of weapons.

The plot is simple: “Woz” is forced to save his wife, J-Woz, after she is kidnapped by street thugs. Teaming up with Vengence, Woz tears up Fusion City in his quest to rescue her.

“Featuring an over-the-top, old school inspired action combined with a retro 8-bit and exciting gritty art style, players will enjoy Woz’s brain power, translator apps, Danny Trejo’s machetes, guns and other crazy upgrades,” a Facebook fan page devoted to the game says.

Other playable characters will include musician Baby Bash and MMA World Champion “Suga” Rashad Evans.

Gaming News Headlines – Yahoo! News

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Hope Solo Weds Jerramy Stevens Amid Assault Allegations?

By Dahvi Shira

11/14/2012 at 06:35 PM EST

Jerramy Stevens and Hope Solo

NFL/Getty; Jeff Vinnick/Getty

One day after former Seattle Seahawks tight end Jerramy Stevens was arrested on suspicion of assaulting his fiancée, U.S. women's soccer team goalkeeper Hope Solo, the pair reportedly tied the knot.

"Confirmed," Sportsradio 950 AM and 102.9 FM radio host Dave Mahler Tweeted on Tuesday. "Jerramy Stevens and Hope Solo were married tonight. Events of yesterday morning didn't change plans."

The pair, who had only been dating for about two months, applied for a marriage license last Thursday. According to court documents, the athletes were arguing over whether to wed in Florida or Washington State.

Stevens, 33, was reportedly released from custody by a Kirkland, Wash., Municipal Court judge on Tuesday after determining there wasn't enough evidence to hold the former football star.

All of the former Dancing with the Stars contestant's social media pages have gone silent since Nov. 6., and calls to her rep have not been returned.

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New gene triples risk for Alzheimer's disease

Scientists have identified a new gene variant that seems to strongly raise the risk for Alzheimer's disease, giving a fresh target for research into treatments for the mind-robbing disorder.

The problem gene is not common — less than 1 percent of people are thought to have it — but it roughly triples the chances of developing Alzheimer's compared to people with the normal version of the gene. It also seems to harm memory and thinking in older people without dementia.

The main reason scientists are excited by the discovery is what this gene does, and how that might reveal what causes Alzheimer's and ways to prevent it. The gene helps the immune system control inflammation in the brain and clear junk such as the sticky deposits that are the hallmark of the disease. Mutations in the gene may impair these tasks, so treatments to restore the gene's function and quell inflammation may help.

"It points us to potential therapeutics in a more precise way than we've seen in the past," said Dr. William Thies, chief medical and scientific officer of the Alzheimer's Association, which had no role in the research. Years down the road, this discovery will likely be seen as very important, he predicted.

It is described in a study by an international group published online Wednesday by the New England Journal of Medicine.

About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.

Until now, only one gene — ApoE — has been found to have a big impact on Alzheimer's risk. About 17 percent of the population has at least one copy of the problem version of this gene but nearly half of all people with Alzheimer's do. Other genes that have been tied to the disease raise risk only a little, or cause the less common type of Alzheimer's that develops earlier in life, before age 60.

The new gene, TREM2, already has been tied to a couple other forms of dementia. Researchers led by deCODE Genetics Inc. of Iceland honed in on a version of it they identified through mapping the entire genetic code of more than 2,200 Icelanders.

Further tests on 3,550 Alzheimer's patients and more than 110,000 people without dementia in several countries, including the United States, found that the gene variant was more common in Alzheimer's patients.

"It's a very strong effect," raising the risk of Alzheimer's by three to four times — about the same amount as the problem version of the ApoE gene does, said Dr. Allan Levey, director of an Alzheimer's program at Emory University, one of the academic centers participating in the research.

Researchers also tested more than 1,200 people over age 85 who did not have Alzheimer's disease and found that those with the variant TREM2 gene had lower mental function scores than those without it. This adds evidence the gene variant is important in cognition, even short of causing Alzheimer's.

"It's another piece in the puzzle. It suggests the immune system is important in Alzheimer's disease," said Andrew Singleton, a geneticist with the National Institute on Aging, which helped pay for the study.

One prominent scientist not involved in the study — Dr. Rudolph Tanzi, a Harvard Medical School geneticist and director of an Alzheimer's research program at Massachusetts General Hospital — called the work exciting, but added a caveat.

"I would like to see more evidence that this is Alzheimer's" rather than one of the other dementias already tied to the gene, Tanzi said. Autopsy or brain imaging tests can show whether the cases attributed to the gene variant are truly Alzheimer's or misdiagnosed, he said.

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Online:

Medical journal: http://www.nejm.org

Alzheimer's info: http://www.alzheimers.gov

Alzheimer's Association: http://www.alz.org

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Marilynn Marchione can be followed at http://twitter.com/MMarchioneAP

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Wall Street drops on deficit, Middle East concerns

NEW YORK (Reuters) - Stocks slid on Wednesday with declines accelerating after President Barack Obama set up a drawn-out fight over the fiscal cliff when he stuck to his pledge to raise taxes on the wealthy, and as violence increased in the Middle East.

Obama, in his first press conference since re-election, held to his position that marginal tax rates will have to rise to tackle the nation's deficits.

With talks over solving the U.S. "fiscal cliff" in early stages, investors are reacting to the uncertainty by shedding positions.

"I think we will have a last-minute cliffhanger solution," said Michael Cheah, portfolio manager at SunAmerica Asset Management in Jersey City, New Jersey, about a deal to avoid the so-called cliff.

"In the meantime, the market is going to get punched every day."

Without a deal, a series of mandated tax hikes and spending cuts will start to take effect early next year that could push the U.S. economy into a recession.

Taxes on capital gains and dividends could rise as part of the negotiations, pushing investors to sell this year and pay lower taxes on their gains.

Adding to the selling pressure, Israel launched a major offensive against Palestinian militants in Gaza, killing the military commander of Hamas in an air strike and threatening an invasion of the enclave. Egypt said it recalled its ambassador from Israel in response.

"We know Europe's in trouble, China's slowing down ... and now you've got the Middle East flaring up again. It's all hitting at once, and obviously, the market is taking a 'sell first, ask questions later' approach," said Ryan Detrick, senior technical strategist at Schaeffer's Investment Research in Cincinnati.

Industrial shares led the decline, dragged lower in part by a 1 percent spike in crude prices after the Israeli offensive on Gaza. The S&P industrial sector index <.gspi> fell 2.5 percent.

Wall Street had opened higher after Dow component Cisco Systems Inc reported first-quarter earnings and revenue late Tuesday that beat expectations, driving its stock up 4.8 percent to $17.66. But the positive momentum was short-lived.

The Dow Jones industrial average <.dji> fell 185.23 points, or 1.45 percent, to 12,570.95 at the close. The S&P 500 <.spx> dropped 19.04 points, or 1.39 percent, to 1,355.49. The Nasdaq Composite <.ixic> lost 37.08 points, or 1.29 percent, to 2,846.81.

Both the Dow industrials and the Nasdaq ended at their lowest levels since late June.

The S&P 500 has fallen 5.1 percent in the six sessions since election night. Wednesday marked the benchmark index's lowest close since July 25.

The Russell 2000 <.rut> tumbled 2 percent. The Dow Jones Transportation average <.djt> slid 2.6 percent. FedEx Corp shares dropped 3.7 percent to $87.12. Bank of America shares lost 3.6 percent to $8.99.

In contrast, Facebook shares jumped 12.6 percent to $22.36 as investors were relieved that expiring trading restrictions on a huge block of shares did not trigger an immediate wave of insider selling.

Teen clothing retailer Abercrombie & Fitch Co jumped 34.4 percent to $41.92 after the company reported unexpectedly improved third-quarter results and a full-year outlook that exceeded Wall Street's forecasts.

About 7.53 billion shares changed hands on the New York Stock Exchange, the Nasdaq and NYSE MKT, more than the daily average so far this year of about 6.51 billion shares.

On the NYSE, decliners outnumbered advancers by a ratio of almost 9 to 1. On the Nasdaq, about four stocks fell for every one that rose.

(Reporting by Rodrigo Campos; Additional reporting by Steven C. Johnson and Leah Schnurr; Editing by Jan Paschal)

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Israel hammers Hamas in Gaza offensive

GAZA (Reuters) - Israel launched a major offensive against Palestinian militants in Gaza on Wednesday, killing the military commander of Hamas in an air strike and threatening an invasion of the enclave that the Islamist group vowed would "open the gates of hell".

The onslaught shattered hopes that a truce mediated on Tuesday by Egypt could pull the two sides back from the brink of war after five days of escalating Palestinian rocket attacks and Israeli strikes at militant targets.

Operation "Pillar of Defence" began with a surgical strike on a car carrying the commander of the military wing of Hamas, the Iranian-armed Islamist movement which controls Gaza and dominates a score of smaller armed groups.

Within minutes of the death of Ahmed Al-Jaabari, big explosions shook Gaza as the Israeli air force struck at selected targets just before sundown, blasting plumes of smoke and debris high above the crowded city.

Panicking civilians ran for cover and the death toll mounted quickly. Ten people including three children were killed, the health ministry said, and about 40 were wounded. Also among the dead were an 11-month-old baby and a woman pregnant with twins.

Army tanks shelled border areas of Gaza in south and the Israeli navy shelled a Hamas security position from the sea.

Hamas stuck back, firing at least four Grad rockets at the southern city of Beersheba in what it called its initial response. Israel reported damage but no casualties. Its 'Iron Dome' interceptor defence knocked out a dozen rockets in flight.

The escalation in Gaza came in a week when Israel fired at Syrian artillery positions it said had fired into the Israeli-annexed Golan Heights amid a civil war in Syria that has brought renewed instability to neighboring Lebanon.

Egypt, whose new Islamist government pledged to honor the 1979 peace treaty with Israel, condemned the raids as a threat to regional security, recalled its ambassador from Israel and called for an emergency session of the U.N. Security Council.

Egyptian President Mohamed Mursi's predecessor Hosni Mubarak twice withdrew his ambassador, with no lasting effect. But Israel will be watching for signs of a more aggressive approach by the Islamist leader that could imperil their ties.

Mursi has said of the Palestinians that "our blood is their blood" and Egypt may not "accept what was accepted before".

Russia called for an end to the raids. Arab League foreign ministers planned to meet on Saturday to discuss the crisis.

DOZENS OF TARGETS

A second Gaza war has loomed on the horizon for months as waves of Palestinian rocket attacks and Israeli strikes grew increasingly more intense and frequent.

Israel's Operation Cast Lead in 2008-2009 began with a week of air attacks and shelling, followed by a land invasion of the blockaded coastal strip, sealed off at sea by the Israeli navy. Some 1,400 Palestinians were killed and 13 Israelis died.

The Israel Defence Forces said it had targeted dozens of Hamas's medium range (up to 40km) underground rocket launch and infrastructure sites in Wednesday's strikes.

"This has significantly damaged the rocket launch capabilities as munitions warehouses owned by Hamas and other terror organizations were targeted. In addition, Israeli Navy soldiers targeted several Hamas terror sites stationed along the shoreline of the Gaza Strip," it said in a statement.

The Hamas internal security headquarters in southern Gaza was destroyed. There were no injuries because it had been evacuated. After dark, Gaza looked like a ghost city, with no traffic and no people in the streets, no shops open, no electric lights on.

KILLED IN HIS CAR

Hamas said Jaabari, who ran the organization's armed wing, Izz el-Deen Al-Qassam, died along with a Hamas photographer when their car was blown apart by an Israeli missile.

The charred wreckage of a car could be seen belching flames, as emergency crews picked up what appeared to be body parts.

Israel confirmed it had carried out the attack and announced there was more to come. Reuters witnesses saw Hamas security compounds and police stations blasted apart.

"Today we relayed a clear message to the Hamas organization and other terrorist organizations," Prime Minister Benjamin Netanyahu said. "And if there is a need, the IDF (Israel Defence Forces) is prepared to broaden the operation. We will continue to do everything in order to protect our citizens."

Immediate calls for revenge were broadcast over Hamas radio.

"The occupation has opened the gates of hell," Hamas's armed wing said. Smaller groups also vowed to strike back.

"Israel has declared war on Gaza and they will bear the responsibility for the consequences," Islamic Jihad said.

Southern Israeli communities within rocket range of Gaza were on full alert, and schools were ordered closed for Thursday. About one million Israelis live in range of Gaza's relatively primitive but lethal rockets, supplemented in recent months by longer-range, more accurate systems.

"The days we face in the south will, in my estimation, prove protracted," Brigadier-General Yoav Mordechai, Israel's chief military spokesman, told Channel 2 TV.

The Israeli cabinet gave preliminary authorization for the mobilization of military reserves if required, Netanyahu's office said.

Asked if Israel might send in ground forces, Mordechai said: "There are preparations, and if we are required to, the option of an entry by ground is available."

OBAMA BRIEFED

Israeli President Shimon Peres briefed U.S. President Barack Obama on the operation, Peres's office said. He told Obama that Jaabari was a "mass-murderer" and his killing was Israel's response to Palestinian rocket attacks from Gaza.

"Israel is not interested in stoking the flames, but for the past five days there has been constant missile fire at Israel and mothers and children cannot sleep quietly at night," said Peres, who visited the border town of Sderot earlier.

In the flare-up that was prelude to Wednesday's offensive, more than 115 missiles were fired into southern Israel from Gaza and Israeli planes launched numerous strikes.

Seven Palestinians, three of them gunmen, were killed. Eight Israeli civilians were hurt by rocket fire and four soldiers wounded by an anti-tank missile.

The leader of Hamas in the Gaza Strip, Ismail Haniyeh, called on Arab states, especially Egypt, to halt the assault. The six-nation Gulf Cooperation Council said the U.N. Security Council should put pressure on Israel to stop its attacks.

Israel holds a general election on January 22 and Netanyahu has pledged to retaliate harshly against Hamas. But Israel is also wary of the reaction from Mursi's Egypt, whose ruling Muslim Brotherhood is the spiritual mentor of Hamas.

Hamas has been emboldened by its rise to power, viewing Mursi as a "safety net" who will not permit a second Israeli thrashing of Gaza, home to 1.7 million Palestinians.

Hamas is also supported by Iran, which Israel regards as a rising threat to its own existence due to its nuclear program.

Helped by the contraband trade through tunnels from Egypt, Gaza militias have smuggled in longer-range rockets.

But their estimated 35,000 Palestinian fighters are still no match for Israel's F-16 fighter-bombers, Apache helicopter gun ships, Merkava tanks and other modern weapons systems in the hands of a conscript force of 175,000, with 450,000 in reserve.

(Additional reporting by Dan Williams, Crispian Balmer and Ori Lewis in Jerusalem; Writing by Douglas Hamilton; Editing by Giles Elgood)

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RIM sees BB10 devices in stores soon after launch

WATERLOO, Ontario (Reuters) – Research In Motion is confident its new BlackBerry 10 devices will be 100 percent ready for the January 30 launch and available in stores “not too long after” that, Chief Operating Officer Kristian Tear said on Tuesday.

“We’re working hard right now to make sure all the bits and pieces and all the details are in place for the date, when the devices will be available for consumers and enterprises,” Tear told Reuters in an interview.

RIM, which virtually invented the concept of mobile email with its first line of BlackBerry devices more than a decade ago, was roundly criticized for the botched 2011 launch of its PlayBook tablet computer, which RIM had hoped would compete with Apple’s blockbuster iPad.

The PlayBook looked pretty and had top-of-the-line hardware. But its software was far from complete at the launch and needed multiple updates.

The device also lacked the library of apps available on the iPad and on devices that run on Google Inc’s competing Android operating system.

RIM says its the new devices will be faster and smoother than its existing phones and have a large catalog of applications that are crucial to the success of any smartphone.

The company hopes the new devices will allow it to claw back some of the market share it has lost to Android and Apple phones.

Tear said RIM has used input from current BlackBerry users to influence the design of the new devices, The new phones both build on the strengths of RIM’s existing operating system and improve on its weak points, he said.

RIM last month began carrier testing on the new devices, with an initial rollout to more than 50 carriers. Tear, who joined RIM a few months ago from Sony Mobile Communications, said RIM was expanding that to a wider group of carriers across the globe.

“We submitted to 50 carriers to begin with, and obviously that number is increasing as we move forward,” he said. “Our ambition is to make this a global launch, everything will not happen at the same time, but it will be a global launch.”

RIM has said it initially plans to roll out a high-end touchscreen version of the device. Phones with the mini QWERTY keyboards that many long-time BlackBerry users adore will come a few weeks later, while lower-end versions of both devices will be launched later in the year.

The company has yet to say exactly when the devices will be available in stores worldwide or how much they will cost.

“We have to agree with carriers as well on what they want to announce when, so it’s not absolutely to our own discretion,” Tear said.

COST CUTTING

RIM, whose share price has fallen more than 90 percent from a 2008 peak around $ 148, is part way through a major restructuring, as it seeks to trim costs in the run-up to the launch of the new devices.

The company, which has also said it is examining its strategic options, is lowering operating costs by about $ 1 billion and cutting about 5,000 jobs, or about 30 percent of its workforce, by the time its fiscal year ends in early March.

“We are on track to deliver on that,” said Tear. “It is an ongoing process, when it comes to efficiencies and costs.”

RIM’s Chief Legal Officer Steve Zipperstein said the company is pushing ahead with its strategic review.

“The process is ongoing and it continues to be a focus on RIM’s senior management, but we have nothing to report at this moment,” said Zipperstein.

RIM shares, which have risen slightly over the last couple of months in the run-up to the launch of BB10 devices, closed 4.7 percent lower at $ 8.40 on Nasdaq. RIM’s Toronto-listed shares fell by a similar margin to C$ 8.40.

(Reporting by Euan Rocha; Editing by Janet Guttsman, Leslie Adler and Tim Dobbyn)

Gadgets News Headlines – Yahoo! News

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John McAfee: I'm Innocent of Murder

By Johnny Dodd

11/13/2012 at 07:00 PM EST

Goateed, tattooed millionaire software pioneer John McAfee, who is on the run from police in Belize after the murder of his neighbor, claims that the authorities are trying to pin the killing on him.

"They will kill me if they find me," McAfee, whose whereabouts are still unknown, tells Wired magazine. "They've been trying to get me for months. They want to silence me."

In the interview, the 67-year-old McAfee detailed how he hid from a contingent of police who showed up at his one-acre beachfront estate shortly after the body of Gregory Faull, 52, was discovered by a housekeeper on Nov. 11 with a bullet in the back of his head.

McAfee, who insists he has nothing to do with the Faull's killing, claims to have eluded authorities by burying himself in the sand and placing a box over his head so that he could breathe.

"It was extraordinarily uncomfortable," he tells Wired. When asked about his neighbor's murder, he insists he knew "nothing – other than I heard he had been shot."

A spokesman for police in Belize says that the local authorities simply want to speak with McAfee about Faull's murder.

"It would be quite nice for him to come in and answer some of the questions that could lead to the closure of this case," spokesman Raphael Martinez tells Reuters. "He is not wanted for murder, but he is wanted for questioning as a person of interest."

McAfee's current predicament is a sad twist for the man regarded as one of Silicon Valley's first Internet entrepreneurs to strike it big.

Two years after taking his anti-virus software company public in 1992, he sold the firm for a reported $100 million, then dabbled in everything from teaching yoga to creating one of the first online instant messaging services before moving to Belize in 2008.

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Microsoft leads Wall Street lower, but retailers gain

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